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Head of Data Science

NMD Pharma A/S
Aarhus N eller København Ø

Senior Director, Statistical Science and Clinical Data Management

Aarhus, Denmark (preferred), with flexibility for Copenhagen, broader Europe, or the United States.

About NMD Pharma

NMD Pharma is a clinical-stage biotech company dedicated to developing novel and improved treatments for people living with neuromuscular diseases. The company is advancing a first-in-class platform of small molecule therapies targeting the skeletal muscle chloride ion channel (ClC-1) to improve muscle function and quality of life for patients with significant unmet medical needs.

Headquartered in Aarhus, Denmark, NMD Pharma combines deep scientific expertise in muscle physiology and neuromuscular disorders with a collaborative and entrepreneurial culture focused on advancing innovative therapies through clinical development.

The Position

Reporting to the Chief Medical Officer, the Head of Data Science will lead the statistical science, statistical programming, and clinical data management function across NMD Pharma’s clinical development portfolio. This is a senior sponsor-side leadership role responsible for building and directing the department, setting standards, overseeing external partners, and ensuring that clinical data and analyses are scientifically robust, decision-ready, and suitable for regulatory use.

You will define the statistical and clinical data strategy across programs and trials, provide strategic input into study design and development planning, and ensure high-quality delivery through a lean, outsourced operating model. You will work closely with cross-functional clinical development colleagues, as well as external CROs and specialist vendors.

Key Responsibilities

  • Own statistical strategy and clinical trial design, including estimands, hypotheses, endpoints, sample size assumptions, randomisation, interim analyses, multiplicity control, and statistical decision criteria.
  • Ensure clinical data are collected, governed, and analysis-ready through oversight of data management, database design, data standards, medical coding, data cleaning, reconciliation activities, and database lock readiness.
  • Lead the development and execution of statistical analyses, including SAPs, analysis datasets, tables, listings, figures, and validated outputs supporting clinical interpretation and regulatory submissions.
  • Ensure data integrity, statistical computing governance, and submission readiness through oversight of CDISC standards, programming quality, vendor performance, traceability, documentation, integrated summaries, and inspection-ready clinical data and analyses.
  • Translate efficacy, safety, exposure-response, subgroup, sensitivity, and exploratory analyses into clear evidence packages that inform development decisions, governance, regulatory interactions, and submissions.

Qualifications & Experience

  • MSc or PhD in Biostatistics, Statistics, Data Science, Mathematics, or related quantitative discipline; PhD preferred
  • Typically 9+ years of relevant biotech, pharma, or CRO experience, including substantial sponsor-side clinical development experience
  • Senior-level leadership of statistical strategy and delivery for interventional trials, including late-stage, pivotal, or registrational studies
  • Experience overseeing clinical data management and statistical programming in an outsourced or hybrid operating model
  • Strong understanding of ICH E9(R1), estimands, missing data, multiplicity, longitudinal analyses, interim analyses, DMC support, and regulatory expectations.
  • Experience contributing to FDA and/or EMA interactions, briefing packages, regulatory responses, and clinical submission deliverables
  • Familiarity with CDISC, SDTM, ADaM, SAS and/or R, programming QC, validated computing environments, and traceable submission-ready data packages
  • Line management, functional leadership, or matrix leadership experience is strongly preferred

Personal Competencies

  • You combine scientific rigour, pragmatic execution, and senior stakeholder leadership while remaining sufficiently hands-on to ensure quality.
  • Strategic and accountable leader able to build and scale a fit-for-purpose function in a growing biotech company
  • Clear communicator who translates statistical concepts, uncertainty, and development implications for non-statistical stakeholders
  • Sound judgement balancing scientific rigour, operational feasibility, regulatory expectations, timelines, and decision needs
  • Collaborative partner across clinical, regulatory, safety, clinical pharmacology, operations, quality, and external vendors
  • Structured, quality-focused, proactive, and comfortable combining strategic leadership with practical problem solving

Why Join NMD Pharma?

This is an opportunity to shape and lead a core development department at a clinical-stage company advancing a late-stage neuromuscular development program with meaningful potential patient impact.

At NMD Pharma, you will join a collaborative and science-driven organisation where you can influence development strategy, work closely with senior leadership, and contribute directly to the company’s future growth and regulatory readiness.

Application

Please submit your application and CV as soon as possible. Applications are reviewed on an ongoing basis.

NMD Pharma is committed to creating an inclusive workplace and welcomes applications from all qualified candidates.

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