Drug substance specialist – small molecules, NMD Pharma

NMD Pharma is a clinical-stage biotechnology company dedicated to developing novel therapies to restore skeletal muscle health to enable better lives. Our lead development candidate, ignaseclant (formerly NMD670), is a first-in-class skeletal muscle-targeted therapy currently in clinical development across Charcot-Marie-Tooth disease (CMT), generalized myasthenia gravis (gMG) and spinal muscular atrophy (SMA).

NMD Pharma is at a pivotal moment in our journey, and we are expanding our team to support the next stage of clinical development and company growth. We are seeking a motivated and highly skilled senior drug substance specialist to join us at this exciting stage in our development and contribute towards our mission of bringing life-changing therapies to patients living with neuromuscular diseases.

Based at either NMD Pharma's headquarters in Aarhus, Denmark, or our office in Copenhagen, Denmark, the right individual will thrive in a dynamic setting of a clinical-stage biotech and share our common purpose to help patients with high unmet medical needs.

As a drug substance specialist, you will use your thorough understanding of chemistry and proven track record of successfully leading the drug substance part of projects. Engagement and a positive mindset, combined with scientific integrity and excellent communication skills, will be essential for this role. You will be a key member of a skilled CMC team.

Key responsibilities

Your main responsibilities will be to:

• Lead the drug substance development program for ignaseclant from preparation for phase 3 until commercialization.
• Function as drug substance lead on other small molecule drug projects, starting from candidate selection and vendor selection.
• Shape the phase-based drug substance development package required to ensure a robust manufacturing process, a prerequisite for regulatory approval.
• Establish and maintain strong collaboration with our CDMOs.
• Manage, coordinate and assess outsourced activities to ensure high quality and timely execution.
• Prepare and review regulatory documentation (IND, CTA, NDA, IB etc.) as well as to respond to questions from authorities.
• Participate in various cross-functional collaborations.

Qualifications

To thrive and succeed in this position we expect you to have:

• A university degree with focus on chemistry (chemistry, chemical engineering, pharmaceutical science, or similar). A PhD degree within a relevant discipline will be an advantage.
• Strong track record as drug substance lead within small molecules in the pharmaceutical industry.
• Comprehensive understanding of ICH and other relevant guidelines.
• Excellent people skills to facilitate interactions.
• Excellent oral and written English communication skills.
• Ability to manage ambiguity - think critically, and make sound, risk-based scientific and business decisions when there is limited information.
• Ability to be flexible and to adapt to a changing environment.
• Demonstrated ability to work both independently and as a strong collaborative member of diverse teams.
• An open, confident attitude as well as experience in balancing big picture thinking with detailed analysis.
• Willingness to travel to CDMOs and other NMD Pharma sites.

What we offer

A competitive salary package and opportunities for professional development in a collaborative and innovative work environment.

You will join a focused biotech organization where scientific rigour is highly valued and where your contributions will directly influence product development. You will be part of a transformative environment that demands precision, clarity, and adaptability.

Equal opportunities

NMD Pharma welcomes diverse candidates: The company is committed to providing equal opportunities for all candidates.

How to apply

Please submit your CV and cover letter via our recruitment portal on Jobindex. Applications will be reviewed on an ongoing basis, and we encourage you to submit your application today to avoid missing out on this opportunity. If you have any questions please feel free to contact Maja Nielsen, People & Culture Director at mbn@nmdpharma.com

Information about NMD Pharma is available at our website www.nmdpharma.com and on our LinkedIn page https://www.linkedin.com/company/nmdpharma/

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