Experienced Organic Chemist

Join our passionate Copenhagen chemistry team and bring new therapies to life through organic synthesis

Orbis Medicines is a pioneering biotech company dedicated to the future of drug discovery by leveraging chemistry and data-driven approaches to transform the treatment landscape. We are looking for an experienced organic synthesis chemist to join our experienced chemistry team and well-equipped synthesis lab in Copenhagen, DK, where you will contribute to the discovery and development of innovative therapeutic solutions. You will be working in a team that is responsible for designing and developing novel synthetic routes for macrocycles, building blocks, including non-natural amino acids and peptoids. We work with both solution and solid phase synthesis and implement new chemistries into Orbis’ synthesis platform.

As a key member of the chemistry team, you will:

• Develop synthetic routes for novel building blocks, including non-natural amino acids.
• Synthesize non-peptidic building blocks, peptidomimetic replacements, and macrocycles with minimized peptidic characteristics.
• Lead the synthesis of macrocycles in the hit-to-lead and lead optimization phases and support candidate development.
• Contribute to the integration of new building blocks into Orbis’ synthesis platform.
• Manage and perform the upscaling of building blocks, advanced intermediates, and final compounds from milligram to gram scale.
• Have a proactive role in having a safe, up-to-date, and well-functioning chemistry lab.
• Generate, manage, analyze, and maintain critical data in a highly organized manner.
• Be working in cross-functional project teams as subject matter expert.
• Be involved in CRO collaboration.

The successful candidate has:

• PhD in chemistry or pharmaceutical science with focus on organic synthesis
• Pharma industry experience as a synthetic organic chemist.
• You have been working in several drug discovery projects, across hit-to-lead, lead optimization, and candidate nomination projects in an industry setting.
• You are very motivated by having a active lab role.

About Orbis Medicines

Joining Orbis Medicines means becoming part of a fast-growing biotech start-up revolutionizing the possibilities of oral macrocycle therapies with our next generation nGen platform. With the recent closure of an EUR 90 million Series A funding round, we are well-positioned for significant growth and long-term success. Orbis Medicines is supported by top-tier international investors Novo Holdings, Forbion, NEA, Eli Lilly and Company, Cormorant and the Export and Investment Fund of Denmark. Endorsement by these leading biotech investors speaks to the strength of our science and our potential to bring innovative therapies to patients.

Our new R&D site in Copenhagen embraces a team of 25 experienced technical professionals and scientists, and together with our colleagues in Lausanne CH, the company has expanded to more than 40 employees within the last 6 months.

We offer the excitement of a start-up, opportunities for professional growth, and the opportunity to be at the forefront of biotech innovation.
Be part of something transformative. Your ideas and contributions will shape the future of medicine.

Visit our website for more details www.orbismedicines.com.

Contact and application

For further information about the position, please contact HR Partner Karin Zimmermann at +45 4082 6146 or VP MedChem & Project Portfolio Daniel Greve at DRG@orbismedicines.com.

You do not need to attach a cover letter, but please include a few sentences about your background and motivation in your CV.

Orbis Medicines is an equal-opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

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